Results 91 to 100 of about 4,114,836 (337)
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Performance Enhancement of Seismically Protected Buildings Using Viscoelastic Tuned Inerter Damper
ActuatorsIn this paper, a viscoelastic (VE) tuned inerter damper (TID) that replaces conventional stiffness and damping elements with a cost-effective VE element is proposed to achieve a target-based improvement of seismically protected buildings.
Pan-Pan Gai +5 more
doaj +1 more source
Delineamento de experimentos em genética genômica Experimental design in genetical genomics
Revista Brasileira de Zootecnia, 2007 Genética genômica é um termo utilizado para representar o estudo de processos genéticos controladores de caracteres fenotípicos de herança complexa, a partir da análise conjunta de informação relativa a fenótipos, estruturas de parentesco, marcadores ...
Guilherme Jordão de Magalhães Rosa
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Highly D‑efficient Weighing Design and Its Construction
Acta Universitatis Lodziensis. Folia Oeconomica, 2017 In this paper, some aspects of design optimality on the basis of spring balance weighing designs are considered. The properties of D‑optimal and D‑efficiency designs are studied.
Bronisław Ceranka, Małgorzata Graczyk
doaj +1 more source
Exponential approximations in optimal design [PDF]
One-point and two-point exponential functions have been developed and proved to be very effective approximations of structural response. The exponential has been compared to the linear, reciprocal and quadratic fit methods.
Belegundu, A. D. +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
OPTIMAL MULTICOMPARTMENTAL EXPERIMENT DESIGN
TASK Quarterly, 1997 Compartmental modelling of biomedical systems, devoted to e.g. optimal therapy design, provides us with a compartmental system, the associated set of differential equations, and a number of unknown parameters.
RENATA KALICKA
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source