Results 101 to 110 of about 12,714,502 (313)
OPTIMAL MULTICOMPARTMENTAL EXPERIMENT DESIGN
TASK Quarterly, 1997 Compartmental modelling of biomedical systems, devoted to e.g. optimal therapy design, provides us with a compartmental system, the associated set of differential equations, and a number of unknown parameters.
RENATA KALICKA
doaj
Integrated Optimal Design of a Passive Wind Turbine System: An Experimental Validation [PDF]
, 2010 This work presents design and experimentation of a full passive wind turbine system without active electronic part(power and control). The efficiency of such device can be obtained only if the system design parameters are mutually adapted through an ...
Sareni, Bruno +4 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
D-optimal Design for Polynomial Regression: Choice of Degree and Robustness [PDF]
In this paper we show that for D-optimal design, departures from the design are much less important than a depar-ture from a model. As a consequence, we propose, based on D-optimality, a rule for choosing the regression degree.
Weinberg Allen, Anna, Antille, Gerard
core
Optimal blocked minimum-support designs for non-linear models
, 2014 Finding optimal designs for experiments for non-linear models and dependent data is a challenging task. We show how the problem simplifies when the search is restricted to designs that are minimally supported; that is, the number of distinct runs ...
van de Ven, P.M., Woods, D.C.
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Optimal Design Methodology for On-shore Hydraulic Pipelines Transporting Spherical Capsules [PDF]
, 2013 The third generation of pipelines comprises of the transportation of capsules that are hollow, water-borne containers, usually spherical or cylindrical in shape, filled with goods.
Paris, Achilleos +3 more
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Optimal discrimination designs [PDF]
We consider the problem of constructing optimal designs for model discrimination between competing regression models. Various new properties of optimal designs with respect to the popular T-optimality criterion are derived, which in many circumstances ...
Dette, Holger, Titoff, Stefanie
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source