Results 151 to 160 of about 4,114,836 (337)

Damage progression from impact in layered glass modeled with peridynamics

Open Engineering, 2012
Bobaru Florin, Ha Youn, Hu Wenke
doaj   +1 more source

Optimal design of minimum-energy pulses for Bloch equations in the case of dominant transverse relaxation [PDF]

, 2009
Dionisis Stefanatos
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A study on the optimal design of isothermal experiments in predictive microbiology. [PDF]

Sci Rep
Muñoz Del Río A, Casero-Alonso V, Amo-Salas M.   +2 more
europepmc   +1 more source

Design Of Statistically Optimal Morphological Operators

, 2000
Júnior Barrera, Edward R. Dougherty
openalex   +1 more source

Solution for Optimal Design Parameters of Desktop Based on Multi-objective Programming [PDF]

, 2016
Han Dong
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A Computational Journey Toward an Optimal Design for Metamaterial Epicardial Passive Sleeves. [PDF]

Adv Healthc Mater
Naeini V, Mendiola EA, Rafsanjani A, Coulter FB, Xiang Q, Zhang J, Vanderslice P, Serpooshan V, Avazmohammadi R.   +8 more
europepmc   +1 more source

Optimum design of E×B mass separator in three dimensions

, 2008
Wenping Li, Han Li, Wenqi Gu
openalex   +1 more source