Results 101 to 110 of about 1,250,546 (301)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Optimal Capacity Planning Method for Distributed Photovoltaics Considering the User Grid Connection Locations

open access: yesEnergies
To address the conflicts between high-penetration distributed photovoltaics (PV) integration causing voltage limit violations, reverse power flow issues, and the grid connection needs of industrial and commercial users, this paper proposes an optimal ...
Jingli Li   +7 more
doaj   +1 more source

Determining optimal locations for blood distribution centers. [PDF]

open access: yesTransfusion, 2022
Wemelsfelder ML   +4 more
europepmc   +1 more source

Statistical Methodology for Optimal Sensor Locations for Damage Detection in Structures [PDF]

open access: yes, 1998
A Bayesian statistical methodology is presented for optimally locating the sensors in a structure for the purpose of extracting the most information about the model parameters which can be used in model updating and in damage detection and ...
Beck, James L.   +2 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Human Pose Estimation using Deep Consensus Voting

open access: yes, 2016
In this paper we consider the problem of human pose estimation from a single still image. We propose a novel approach where each location in the image votes for the position of each keypoint using a convolutional neural net.
DH Ballard   +7 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Optimal Sensor Locations for Structural Identification [PDF]

open access: yes
The optimum sensor location problem, OSLP, may be thought of in terms of the set of systems, S, the class of input time functions, I, and the identification algorithm (estimator) used, E.
Garba, J., Udwadia, F. E.
core   +1 more source

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