Results 71 to 80 of about 1,250,546 (301)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Optimal locations of establishing smoking cessation services for cancer patients in Crete, Greece

open access: yesTobacco Prevention and Cessation, 2017
Introduction To identify the optimum geographic locations of establishing smoking cessation services for cancer patients in Crete. Material and Methods Data (1992-2013) for selected tobacco induced cancers (lung, oral cavity and pharynx, nasal cavity ...
Dimitra Sifaki-Pistolla   +6 more
doaj   +1 more source

Reallocating Multiple Facilities on the Line

open access: yes, 2019
We study the multistage $K$-facility reallocation problem on the real line, where we maintain $K$ facility locations over $T$ stages, based on the stage-dependent locations of $n$ agents. Each agent is connected to the nearest facility at each stage, and
Fotakis, Dimitris   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Identifying optimal locations for street experiments: A digital case study in Bologna

open access: yesJournal of Urban Mobility
This paper examines the integration of digital urban planning tools to identify optimal locations for street experiments, considering multiple parameters.
Corneel Casier   +7 more
doaj   +1 more source

Comparing population and incident data for optimal air ambulance base locations in Norway

open access: yesScandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2018
Background Helicopter emergency medical services are important in many health care systems. Norway has a nationwide physician manned air ambulance service servicing a country with large geographical variations in population density and incident ...
Jo Røislien   +6 more
doaj   +1 more source

Optimal number and locations of automatic vehicle identification sensors considering link travel time estimation

open access: yesIET Intelligent Transport Systems, 2023
The problem of optimally locating Automatic Vehicle Identification (AVI) sensors on a traffic network for travel time estimation has been a topic of growing interests in recent years.
Yiting Zhu, Zhaocheng He, Xinshao Zhang
doaj   +1 more source

Optimal Locations and Inner Products

open access: yesJournal of Mathematical Analysis and Applications, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Optimization of a truck-drone in tandem delivery network using k-means and genetic algorithm

open access: yesJournal of Industrial Engineering and Management, 2016
Purpose: The purpose of this paper is to investigate the effectiveness of implementing unmanned aerial delivery vehicles in delivery networks. We investigate the notion of the reduced overall delivery time, energy, and costs for a truck-drone network by ...
Sergio Mourelo Ferrandez   +4 more
doaj   +1 more source

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