Results 51 to 60 of about 6,268,147 (307)

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Reliability-Based Opportunistic Maintenance Modeling for Multi-Component Systems with Economic Dependence under Base Warranty

Discrete Dynamics in Nature and Society, 2021
Maintenance usually plays a key role in controlling a multi-component production system within normal operations. Furthermore, the failure of components in the production system will also cause large economic losses for users due to the shutdown ...
Rongcai Wang, Zhonghua Cheng, Enzhi Dong, Chiming Guo, Liqing Rong   +4 more
doaj   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Breeding of zebrafish in the laboratory environment for research development

Bangladesh Journal of Pharmacology, 2017
The zebrafish (Danio rerio) has turn out to be an excellent vertebrate organism for analyzing developmental stages, disease modeling, and screening of drug toxicities due to their minuscule, high fecundity, optical transparency and there close parallels ...
Sang Ho Kim, Chanchal Sharma, Imran Khan, Sun Chul Kang   +3 more
doaj   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source

Generator Maintenance Scheduling Method Using Transformation of Mixed Integer Polynomial Programming in a Power System Incorporating Demand Response

Energies, 2019
Periodic preventive maintenance of generators is required to maintain the reliable operation of a power system. However, generators under maintenance cannot supply electrical energy to the power system; therefore, it is important to determine an optimal ...
Hyung-Chul Jo, Rakkyung Ko, Sung-Kwan Joo   +2 more
doaj   +1 more source

Selection of the optimal maintenance organization for specific purpose devices [PDF]

Serbian Journal of Electrical Engineering, 2014
This paper is a result of a broader study, oriented to optimization of maintenance process for special purpose devices and presents the selection of optimal maintenance variant for selected specific purposes device, using the method of analytic ...
Radonjić Vojkan, Đukić Slobodan, Jovanović Danko, Ćirić Milenko, Petrović Saša   +4 more
doaj   +1 more source

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

Determination of a model of preventive maintenance of special purpose vehicles

Vojnotehnički Glasnik
Introduction/purpose: The aim of this paper is to obtain quantitative and qualitative indicators of vehicle condition and reliability based on operational data which can be used to determine the optimal periodicity of preventive maintenance for special ...
Stojko Lj. Biočanin, Milica S. Timotijević, Željko M. Bulatović, Milan A. Mišić   +3 more
doaj   +1 more source