Results 141 to 150 of about 5,095,233 (306)

Daily operating mode optimization for parabolic trough concentrated solar power station by considering start-up energy consumption

Reli fadian
The start-up energy consumption of parabolic trough concentrated solar power (PTCSP) systems is high due to the characteristics of their daily start-up and shut-down processes.
HE Chunguang, GUO Wei, ZHANG Shunqi, HAN Wei, FU Kangli, FENG Penghui, YAO Mingyu, AN Jiakun   +7 more
doaj   +1 more source

Optimal process mode selection for clone screening.

Acta chimica Slovenica, 2011
Pri izboru produkcijskega klona je potrebno zbrati in ovrednotiti veliko količino podatkov, saj pri izboru uporabljamo različne gojitvene sisteme, kot so na primer ploščice z gojitvenimi jamicami, erlenmajerice, bioreaktorji itd. Obdelava vseh podatkov je ponavadi zelo dolgotrajna in pogosto je potrebno uporabiti različne matematične in statistične ...
Brinc, Matjaž, Kravanja, Zdravko, Rozman Pungerčar, Jerica, Spudić, Vatroslav, Strnad, Jure   +4 more
openaire   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Autoencoder-based conditional optimal transport generative adversarial network for medical image generation

Visual Informatics
Medical image generation has recently garnered significant interest among researchers. However, the primary generative models, such as Generative Adversarial Networks (GANs), often encounter challenges during training, including mode collapse. To address
Jun Wang, Bohan Lei, Liya Ding, Xiaoyin Xu, Xianfeng Gu, Min Zhang   +5 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Optimal mode in a transit corridor

, 2015
https://github.com/luigimoccia/Optimal-mode-in-a-transit-corridor ...
Luigi Moccia
core  

Optimal mode of aortic valve replacement in patients with chronic obstructive pulmonary disease-which helps patients gain more benefit? [PDF]

J Thorac Dis, 2019
Lv WY, Li SJ, Chen M.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Optimal mode for delivery of seasonal malaria chemoprevention in Ouelessebougou, Mali: A cluster randomized trial. [PDF]

PLoS One, 2018
Barry A, Issiaka D, Traore T, Mahamar A, Diarra B, Sagara I, Kone D, Doumbo OK, Duffy P, Fried M, Dicko A.   +10 more
europepmc   +1 more source