Results 101 to 110 of about 1,666,389 (343)

Advanced design for orbital debris removal in support of solar system exploration [PDF]

open access: yes
The development of an Autonomous Space Processor for Orbital Debris (ASPOD) is the ultimate goal. The craft will process, in situ, orbital debris using resources available in low Earth orbit (LEO).

core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

MANURE VALUE, PRICING SYSTEMS, AND SWINE PRODUCTION DECISIONS [PDF]

open access: yes
Based on a swine producer's profit maximization model in which manure value and packers' live market weight pricing systems are considered, the optimal farm inventory and optimal hog market weight are simultaneously solved for scenarios generated from ...
Huang, Haixiao, Miller, Gay Y.
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Optimization and Rule Analysis of Drawdown Level before Flood Season of Longtan Hydropower Station

open access: yesRenmin Zhujiang, 2023
Longtan Hydropower Station is the controlled reservoir of the Hongshui River.It is of significance for flood control,water supply,and power safety to study the optimal drawdown level before flood seasons in this station.Based on analyzing the drawdown ...
LIU Yongqi   +5 more
doaj  

Natural Environmental Service Support to NASA Vehicle, Technology, and Sensor Development Programs [PDF]

open access: yes
The research performed under this contract involved definition of the natural environmental parameters affecting the design, development, and operation of space and launch vehicles. The Universities Space Research Association (USRA) provided the manpower

core   +1 more source

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