Results 81 to 90 of about 1,666,389 (343)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Research on Optimal Operation of Cold-Thermal-Electric Integrated Energy System Considering Source-Load-Storage Multi-Energy Complementarity

open access: yes发电技术, 2020
The integrated energy system (IES) is based on multi-energy complementarity and energy ladder utilization, which will greatly improve the energy utilization of the system and achieve multiple energy flow complementary optimization.
Bin OYANG   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Stochastically ordered subpopulations and optimal burn-in procedure [PDF]

open access: yes
Burn-in is a widely used engineering method which is adopted to eliminate defective items before they are shipped to customers or put into the field operation.
Ji Cha, Maxim S. Finkelstein
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Optimal operation of integrated energy systems incorporating green certificate and carbon trading interaction mechanism

open access: yesZhejiang dianli
To enhance the renewable energy integration capability, economic performance of green electricity, and flexibility in electricity market participation of integrated energy systems (IES), this paper proposes an optimal operation strategy for a green ...
LI Fan   +6 more
doaj   +1 more source

Impact of Demand Response Programs on Optimal Operation of Multi-Microgrid System

open access: yesEnergies, 2018
The increased penetration of renewables is beneficial for power systems but it poses several challenges, i.e., uncertainty in power supply, power quality issues, and other technical problems.
Anh-Duc Nguyen   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy