Results 51 to 60 of about 8,951,053 (252)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Wake‐effect aware optimal online control of wind farms: An explicit solution

open access: yesIET Renewable Power Generation, 2021
Wake effects impose significant aerodynamic interactions among wind turbines. To improve the wind farm operating performance, practical wind farm online control considering wake effects becomes very important.
Kaixuan Chen   +5 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Optimal Connection Voltage of Soft Open Point and Shore-to-Ship Power Converters for Enhanced Capacitive Reactive Power Operation

open access: yesIEEE Access
Soft Open Point and Shore-to-Ship Power applications permit to deploy smart grid infrastructure into distribution and port networks. Both are based on power electronics converters that require an optimal integration to maximize capacitive reactive power ...
Eneko Olea-Oregi   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Linear Quadratic Optimal Modeling for Metro Train Operation and Solving with Interior-point Algorithm

open access: yesKongzhi Yu Xinxi Jishu, 2018
It investigated the energy optimal control problem for metro train operation process and established a linear quadratic optimal model in according to the traction and brake capability, speed limits andpassenger comfort.
FENG Jianghua   +4 more
doaj  

Optimisation of real-time control for hybrid diesel–PV–battery systems

open access: yesInternational Journal of Sustainable Energy, 2017
Hybrid diesel–PV–battery systems are one of the most cost effective options for off-grid power generation. A methodology for the optimal operation of such systems for an off-grid application is proposed in this paper.
Julia Sachs, Kevin Tom, Oliver Sawodny
doaj   +1 more source

Impact of EV charging/discharging strategies on the optimal operation of islanded microgrid

open access: yesThe Journal of Engineering, 2019
This work aims to investigate the impact of electric vehicles (EVs) charging/discharging strategies on the optimal operation of islanded microgrid (MG).
Tanuj Rawat   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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