Results 91 to 100 of about 5,635,969 (342)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
VLSI Placement Optimization Algorithms
Journal of Integrated Circuits and Systems, 2022 Placement is a fundamental optimization step to compute cell locations. The quality of results in Clock Tree Synthesis (CTS) and routing stages is impacted by the placement solution. The placement optimization flow is split into (1)global placement, (2) legalization, and (3) detailed placement.
openaire +1 more source
Optimal Data Placement on Networks With Constant Number of Clients
, 2010 We introduce optimal algorithms for the problems of data placement (DP) and page placement (PP) in networks with a constant number of clients each of which has limited storage availability and issues requests for data objects.
Baev +11 more
core +4 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Uncoded placement optimization for coded delivery [PDF]
2018 16th International Symposium on Modeling and Optimization in Mobile, Ad Hoc, and Wireless Networks (WiOpt), 2018 30 pages, 8 figures, presented in part at IEEE WiOpt ...
Jin, Sian +3 more
openaire +2 more sources
, 2017 We use information theoretic achievable rate formulas for the multi-relay channel to study the problem of as-you-go deployment of relay nodes. The achievable rate formulas are for full-duplex radios at the relays and for decode-and-forward relaying ...
Chattopadhyay, Arpan +3 more
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Fault Current Limiters in Power Systems: A Comprehensive Review
Energies, 2018 Power systems are becoming more and more complex in nature due to the integration of several power electronic devices. Protection of such systems and augmentation of reliability as well as stability highly depend on limiting the fault currents.
Md Shafiul Alam +2 more
doaj +1 more source