Results 111 to 120 of about 5,635,969 (342)

Optimal Placement of IoT-Based Fault Indicator to Shorten Outage Time in Integrated Cyber-Physical Medium-Voltage Distribution Network

open access: yesEnergies, 2020
Traditional fault indicators based on 3G and 4G cannot send out fault-generated information if the distribution lines are located in the system across remote mountainous or forest areas.
Jing Li   +8 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Optimal placement of DG and DSTATCOM for loss reduction and voltage profile improvement

open access: yesAlexandria Engineering Journal, 2017
Due to rapid depletion of fossil fuels availability and huge environmental pollution, focus is now changing from traditional method of power generation to the non-conventional DERs located at distribution voltage level. Technological advancement and more
Fahad Iqbal   +2 more
semanticscholar   +1 more source

Minimal Actuator Placement with Optimal Control Constraints

open access: yes, 2015
We introduce the problem of minimal actuator placement in a linear control system so that a bound on the minimum control effort for a given state transfer is satisfied while controllability is ensured.
Jadbabaie, Ali   +3 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Optimal placement of imperfect water quality sensors in water distribution networks

open access: yesComputers and Chemical Engineering, 2019
Water Distribution Networks (WDNs) are often susceptible to either accidental or deliberate contamination which can lead to poisoned water, many fatalities and large economic consequences.
Casper de Winter   +3 more
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

An Optimization Method for Configuration of Line Terminal Units Based on Topology-Based Data Collection in Low-Voltage Distribution Areas

open access: yesZhongguo dianli
In order to solve the problem of excessive and inefficient allocation of acquisition terminals in the existing low-voltage distribution areas, which leads to high cost of intelligent transformation of the station areas, an optimization method for ...
Guang XU   +6 more
doaj   +1 more source

Optimal Placement of Distribution Generation in Radial Distribution System Using Hybrid Genetic Dragonfly Algorithm

open access: yesTechnology and Economics of Smart Grids and Sustainable Energy, 2021
G. V. N. Lakshmi   +2 more
semanticscholar   +1 more source

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