Results 51 to 60 of about 10,379,454 (251)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Optimal Power Flow Analysis in Power Dispatch for Distribution Networks [PDF]

open access: yes, 2018
This paper presents two applications of Optimal Power Flow analysis for active and reactive power redispatch in medium-voltage distribution networks and shows how this tool can be used to efficiently manage the selection and operation of network ...
Diana Moneta   +9 more
core   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Solving of Optimal Power Flow Problem Including Renewable Energy Resources Using HEAP Optimization Algorithm

open access: yesIEEE Access, 2021
This paper presents a novel endeavor to use the Heap optimization algorithm (HOA) to solve the problem of optimal power flow (OPF) in the electricity networks.
Mohamed A. M. Shaheen   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Blockchain-based Optimal Power Flow Distributed Optimization Algorithm for Power Systems

open access: yesJournal of Harbin University of Science and Technology
In current power systems, the resolution of the Optimal Power Flow (OPF) problem is crucial for ensuring the stable operation and efficiency of the grid.
ZHOU Jia   +4 more
doaj   +1 more source

Linear programming based optimal power flow using second order sensitivities

open access: yes, 1995
For the electric railway traction in Sweden, a system of 130 kV transmission lines connected parallel to the contact lines is being build. Within this system, the generation costs differs only slightly between different nodes with power injections.
Söder, Lennart H.,   +2 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Optimal power flow considering intermittent solar and wind generation using multi-operator differential evolution algorithm

open access: yes
In this paper, a multi-operator differential evolution algorithm (MODE) is proposed to solve the Optimal Power Flow problem, called MODE-OPF. The MODE-OPF utilizes the strengths of more than one differential evolution operator in a single algorithmic ...
Sallam, KM   +11 more
core   +2 more sources

Advances in Transient Stability-Constrained Optimal Power Flow of Power Systems

open access: yesCSEE Journal of Power and Energy Systems
Transient stability-constrained optimal power flow (TSCOPF) optimizes power flow while ensuring stability against potential contingencies. The main challenges faced by TSCOPF are the handling of transient constraints.
Hang Zhang, Yan Xu, Zhao Yang Dong
doaj   +1 more source

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