Results 71 to 80 of about 520,043 (261)

Determination of optimal total area of heat recovery steam generator

open access: yesCase Studies in Thermal Engineering
Heat recovery steam generator (HRSG) plays a critical role in recovering waste heat from exhaust gas in a combined cycle. The performance of the steam cycle in the combined cycle depends on total HRSG area.
Somchart Chantasiriwan
doaj   +1 more source

Optimizing recovery

open access: yes
INTRODUCTION: Even small quantities of prescribed opioids for acute postoperative pain can lead to addiction, hinder recovery, and be unnecessary. This study evaluated whether an opioid-free postoperative pathway following reconstructive urologic surgery increased pain-related patient communication.
Freeman, Samantha   +3 more
openaire   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Innovative Hydrogel Design: Tailoring Immunomodulation for Optimal Chronic Wound Recovery

open access: yesAdvanced Science
Despite significant progress in tissue engineering, the full regeneration of chronic wounds persists as a major challenge, with the immune response to tissue damage being a key determinant of the healing process's quality and duration.
Chun‐Mei Lai   +5 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

Optimal Recovery of Rayleigh‐Wave Overtones by Multi‐Directional Acquisition

open access: yesGeophysical Research Letters
Rayleigh waves are ubiquitously used for subsurface characterization through dispersion curve inversion, whose quality depends on the number of useable overtones.
A. Lellouch, E. Shimony, P. Sinitsyn
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Urban infrastructure recovery strategy under extreme precipitation based on multi-objective optimization algorithm

open access: yesJournal of Hydrology: Regional Studies
Study region: Gulou district, Nanjing, China. Study focus: Facing escalating extreme precipitation and urbanization, urban infrastructure resilience is critical.
Peng Wang   +5 more
doaj   +1 more source

Optimal submerged waterjet for gas recovery based on Arbitrary Lagrange‐Euler

open access: yesEnergy Science & Engineering, 2019
This paper proposes a coupled model of waterjet cutting coal containing gas with the Arbitrary Lagrange‐Euler algorithm assistance. The dynamic evolution of coal damage and the cutting performance under different jet conditions, including jet pattern ...
Long Wang   +4 more
doaj   +1 more source

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