Results 81 to 90 of about 520,043 (261)

Optimal duration of therapy in the recovery period of vestibular diseases

Неврология, нейропсихиатрия, психосоматика, 2014
Dizziness is a common symptom in neurological and general medical practice. In most cases it is caused by diseases of the central or peripheral vestibular system.
M. V. Zamergrad, V. A. Parfenov, N. N. Yakhno   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Erratum to: Optimal adaptive sampling recovery [PDF]

Advances in Computational Mathematics, 2011
We correct the definitions of the quantities of optimal sampling recovery en(W)q and rn(W)q which have been introduced in [1]. All the results and proofs of [1] are unchanged and hold true for the new corrected definitions given below. Recall that the definition of sampling recovery method SB n was given by (1.4) in [1].
openaire   +2 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Island recovery methods considering optimal scheduling of emergency mobile resources

Scientific Reports
In recent years, extreme weather events caused by climate change, such as ice storms, typhoons and earthquakes, have caused increasingly devastating damage to critical energy infrastructure.
Tingjun Li, Xin Chen, Xiaoqing Han, Hao Zhang   +3 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Walsh Spectrum Puncturing Revisited: Toward Automated Linear Key Recovery Attacks

IACR Transactions on Symmetric Cryptology
Linear cryptanalysis has long served as a cornerstone in the security analysis of symmetric-key cryptanalytic primitives. Through more than 30 years of community efforts, it has become routine to use automated tools to search for the optimal linear ...
Chengan Hou, Shuyi Wang, Meicheng Liu
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Valuation of Ecosystem Services Based on EU Carbon Allowances-Optimal Recovery for a Coal Mining Area. [PDF]

Int J Environ Res Public Health, 2022
Krzemień A, Álvarez Fernández JJ, Riesgo Fernández P, Fidalgo Valverde G, Garcia-Cortes S.   +4 more
europepmc   +1 more source