Results 91 to 100 of about 385,762 (339)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Optimal Scheduling of Hydro‐Wind‐Photovoltaic Complementary System Based on Reinforcement Learning‐Proximal Policy Optimization

The Journal of Engineering
The power output of wind power and photovoltaic (PV) features strong stochastic and intermittent characteristics, which increases the difficulty of economic scheduling for the power grid.
Xiaokun Liu, Jian Su, Le Li, Yuanyuan Han, Hongwei Ran, Yuan Wang   +5 more
doaj   +1 more source

INCORPORATION OF WITHIN-SEASON YIELD GROWTH INTO A MATHEMATICAL PROGRAMMING SUGARCANE HARVEST SCHEDULING MODEL [PDF]

This study focuses on the development of a optimal harvest scheduling mathematical programming model which incorporates within-season changes in perennial crop yields.
Champagne, Lonnie P., Legendre, Benjamin L., Salassi, Michael E.   +2 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Experimental Analysis of Algorithms for Coflow Scheduling

, 2016
Modern data centers face new scheduling challenges in optimizing job-level performance objectives, where a significant challenge is the scheduling of highly parallel data flows with a common performance goal (e.g., the shuffle operations in MapReduce ...
CA Phillips, H Ballani, JY Leung, LA Hall, M Alizadeh, M Chowdhury, M Pinedo, M Skutella   +7 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Optimization Pine Plantation Forest Management in Kediri FMU Regional Division II East Java

Jurnal Manajemen Hutan Tropika, 2017
Pine forest management today has not already reached its optimal state. The abnormal pine stand structure will cause a decrease in the production of pine resin.
Andrie Ridzki Prasetyo, Muhamad Buce Saleh, Sudarsono Soedomo   +2 more
doaj   +3 more sources

On the Throughput of Large-but-Finite MIMO Networks using Schedulers

, 2018
This paper studies the sum throughput of the {multi-user} multiple-input-single-output (MISO) networks in the cases with large but finite number of transmit antennas and users.
Alouini, Mohamed-Slim, Makki, Behrooz, Svensson, Tommy   +2 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Source-network-load-storage collaborated two-stage power dispatch of active distribution network with conditional value-at-risk

International Journal of Electrical Power & Energy Systems
The high penetration of distributed wind turbines (WT) and photovoltaics (PV) brings temporal volatility and uncertainty to their output, posing significant challenges to the optimal scheduling of distribution networks.
Shiwei Xia, Yifeng Wang, Xinyuan Hu, Yuting Yan, Mingze Tong, Haowen Liang, Xiaoyun Wu, Jian Huo   +7 more
doaj   +1 more source