Results 51 to 60 of about 2,748,769 (296)

Optimal outpatient appointment scheduling [PDF]

open access: yesHealth Care Management Science, 2007
In this paper optimal outpatient appointment scheduling is studied. A local search procedure is derived that converges to the optimal schedule with a weighted average of expected waiting times of patients, idle time of the doctor and tardiness (lateness) as objective. No-shows are allowed to happen. For certain combinations of parameters the well-known
Kaandorp, G., Koole, G.M.
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Scheduling and control of high throughput screening systems with uncertainties and disturbances

open access: yesProduction and Manufacturing Research: An Open Access Journal, 2022
Based on the existing research work on the modeling and control of cyclically operated high-throughput screening systems, this paper presents the scheduling and control of high-throughput screening systems with uncertainties and disturbances.
Adetola Oke   +3 more
doaj   +1 more source

Scheduling Optimization of Linear Schedule with Constraint Programming

open access: yesComputer-Aided Civil and Infrastructure Engineering, 2018
In recent decades, construction project scheduling optimization has received extensive attention from the research community. However, the most commonly used scheduling approach, the critical path method, is often inapplicable to transportation-type linear projects.
Yuanjie Tang   +4 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Properties of optimal schedules in preemptive shop scheduling

open access: yesDiscrete Applied Mathematics, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Philippe Baptiste   +5 more
openaire   +4 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

An optimal day-ahead scheduling method for power systems considering extreme, unanticipated and dynamic-temporal scenarios

open access: yesZhejiang dianli
Existing optimal scheduling methods cannot cover all unanticipated scenarios. To overcome this limitation, this paper proposes an optimal day-ahead scheduling method that considers extreme, unanticipated and dynamic-temporal scenarios.
SUN Junjie   +5 more
doaj   +1 more source

Group Elevator Peak Scheduling Based on Robust Optimization Model

open access: yesAdvances in Electrical and Computer Engineering, 2013
Scheduling of Elevator Group Control System (EGCS) is a typical combinatorial optimization problem. Uncertain group scheduling under peak traffic flows has become a research focus and difficulty recently.
ZHANG, J., ZONG, Q.
doaj   +1 more source

Home - About - Disclaimer - Privacy