Results 101 to 110 of about 2,940,613 (295)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Systems and Soft ComputingCurrently, traditional scheduling methods are difficult to cope with the increasing demand and complexity of education, especially when dealing with large-scale data, diverse course schedules, and personalized teaching needs.
Lingzhi Yan, Hua Deng
doaj +1 more source
Resource-constrained project scheduling. [PDF]
: Resource-constrained project scheduling involves the scheduling of project activities subject to precedence and resource constraints in order to meet the objective(s) in the best possible way. The area covers a wide variety of problem types.
Herroelen, Willy, Demeulemeester, Erik
core
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Optimal production scheduling for dairy industries [PDF]
, 2005 In this work, a complete two-level framework for use in food and in particular dairy industries is proposed. The specific characteristics of the dairy industry have been taken into consideration, in terms of the behavior of food sales over time and the ...
Patrinos, Panagiotis +3 more
core +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
CSEE Journal of Power and Energy SystemsA regional electricity-heating integrated energy system (REH-IES) can make extensive use of renewable energy sources, realize complementary and coordinated operation of multiple energy sources, reduce carbon emissions and promote the development of zero ...
Houhe Chen +5 more
doaj +1 more source
Comparative Study of Profiled School Scheduling Programs in Lithuania
Informatics in Education, 2005 Solution of the problem of optimal school scheduling is very important to make the work of comprehensive schools more effective. Here the sequence of teaching subjects, regarded as tools, can be changed. One needs to reduce the sum of gaps (“empty” hours)
Rita GAIDUKEVICIENE, Eugenijus KURILOVAS
doaj +1 more source
Integrating nurse and surgery scheduling. [PDF]
Scheduling; Surgery scheduling; International; Theory; Applications; Euro; Researchers;
Belien, Jeroen, Demeulemeester, Erik
core