Results 71 to 80 of about 385,762 (339)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Task scheduling scheme based on improved particle swarm optimization with biological symbiosis mechanism in cloud computing

open access: yesDianxin kexue, 2016
For the issues that the existing task scheduling scheme based on intelligent algorithms can’t obtain the optimal solution in cloud computing and inspired by nature symbiosis,a new task scheduling scheme based on improved particle swarm optimization(PSO ...
Linjie WANG
doaj   +2 more sources

Optimal deadline scheduling with commitment [PDF]

open access: yes2011 49th Annual Allerton Conference on Communication, Control, and Computing (Allerton), 2011
We consider an online preemptive scheduling problem where jobs with deadlines arrive sporadically. A commitment requirement is imposed such that the scheduler has to either accept or decline a job immediately upon arrival. The scheduler's decision to accept an arriving job constitutes a contract with the customer; if the accepted job is not completed ...
Chen, Shiyao, Tong, Lang, He, Ting
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Optimal Scheduling for OFDMA Systems [PDF]

open access: yes2006 Fortieth Asilomar Conference on Signals, Systems and Computers, 2006
We consider a scheduling and resource allocation problem for the downlink of an OFDMA-based wireless network, where the channel estimation error is modeled by a self-noise term in the decoding process. During each time-slot this involves selecting a subset of users for transmission, determining the assignment of available subcarriers to selected users,
Agrawal, Rajeev   +3 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Application of hyperbolic partial differential equations in global optimal scheduling of UAV

open access: yesAlexandria Engineering Journal, 2020
The global optimal scheduling of UAV (unmanned aerial vehicle) navigation channel is studied. Firstly, a multi-channel optimal scheduling mathematical model based on the HPDEs (hyperbolic partial differential equations) wave combination optimization is ...
Chong Tian, Kuo-Chi Chang, JinSong Chen
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

On Optimal Weighted-Delay Scheduling in Input-Queued Switches

open access: yes, 2017
Motivated by relatively few delay-optimal scheduling results, in comparison to results on throughput optimality, we investigate an input-queued switch scheduling problem in which the objective is to minimize a linear function of the queue-length vector ...
Lu, Yingdong   +3 more
core  

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