Influence of Drilling Protocol on Primary Implant Stability Depending on Different Bone Qualities and Implant Macro-Designs, Lengths, and Diameters. [PDF]
Stoilov M +6 more
europepmc +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
High-throughput optimization of antibody production in CHO cells by tuning heavy- and light-chain promoter strength. [PDF]
Rahimi M +4 more
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Re-Innovation in Clinical Trial Designs Based on Precision Therapy. [PDF]
Li S +5 more
europepmc +1 more source
Enhancing sustainable concrete using waste ceramic powder and natural pozzolan through experimental and machine learning approaches. [PDF]
Nasr D, Babagoli R, Dehaghani AK.
europepmc +1 more source
Proceedings of the University of Pennsylvania 16th annual conference on statistical issues in clinical trials: Optimizing dose selection across the clinical trials spectrum. [PDF]
Putt ME, Shaw PA.
europepmc +1 more source
A Biomarker-Based Dose-Schedule Optimization Design for Immunotherapy Trials. [PDF]
Qiu Y, Han Y, Guo B.
europepmc +1 more source
Efficacy and diagnostic yield of 19G <i>versus</i> 22G fine needle biopsy needles in EUS-guided liver biopsy: A systematic review and meta-analysis. [PDF]
Kalsi H +4 more
europepmc +1 more source

