Results 61 to 70 of about 342,776 (277)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

G-Doob-Meyer Decomposition and Its Applications in Bid-Ask Pricing for Derivatives under Knightian Uncertainty

open access: yesJournal of Applied Mathematics, 2015
The target of this paper is to establish the bid-ask pricing framework for the American contingent claims against risky assets with G-asset price systems on the financial market under Knightian uncertainty. First, we prove G-Dooby-Meyer decomposition for
Wei Chen
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Stochastic recursive optimal control problem with obstacle constraint involving diffusion type control

open access: yesAdvances in Difference Equations, 2020
This paper concerns a kind of stochastic optimal control problem with recursive utility described by a reflected backward stochastic differential equation (RBSDE, for short) involving diffusion type control which covers regular control problem, singular ...
Zhenda Xu
doaj   +1 more source

Optimal Stopping with Private Information [PDF]

open access: yesSSRN Electronic Journal, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kruse, Thomas, Strack, Philipp
openaire   +4 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Discounted Optimal Stopping of a Brownian Bridge, with Application to American Options under Pinning

open access: yesMathematics, 2020
Mathematically, the execution of an American-style financial derivative is commonly reduced to solving an optimal stopping problem. Breaking the general assumption that the knowledge of the holder is restricted to the price history of the underlying ...
Bernardo D’Auria   +2 more
doaj   +1 more source

Optimal stopping problems with regime switching: a viscosity solution method [PDF]

open access: yes, 2015
We employ the viscosity solution technique to analyze optimal stopping problems with regime switching. Specifically, we obtain the viscosity property of value functions, the uniqueness of viscosity solutions, the regularity of value functions and the ...
Zhang, Na, Zhang, Yong-Chao
core  

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

On a Class of Optimal Stopping Problems with Mixed Constraints [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2010
Let X(1),X(2),...,X(n) be independent, identically distributed uniform random variables on [0, 1]. We can observe the outcomes sequentially and must select online at least r of them, and, moreover, in expectation at least mu >= r.
F. Thomas Bruss
doaj   +1 more source

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