Exploring Bayesian adaptive designs in multi-arm randomized controlled trials with a patient preference arm. [PDF]
J Biopharm StatBrown AR +5 more
europepmc +1 more source
Advanced Science, EarlyView.A physics‐based framework resolving graphite phase‐separation dynamics establishes a predictive, degradation‐aware fast‐charging methodology for commercial Li‐ion batteries. The resulting model‐informed protocol achieves 20%–80% state‐of‐charge in 14 min while matching the long‐term degradation of a commercial 25‐minute EV strategy.
Marco Lagnoni +10 more
wiley +1 more source
The Consumer's Reservation Price as an Adaptive Aspiration Level. [PDF]
Behav Sci (Basel)van Baal S.
europepmc +1 more source
DNA Nanoarray for Multiplexed RNA Detection With Single‐Molecule Readout
Advanced Science, EarlyView.A carrier‐based DNA nanoarray integrates programmable nucleic acid hybridization with solid‐state nanopore readout for direct RNA detection at single‐molecule resolution. A ternary encoding system enables 27 carriers with 81 addressable sensing sites, allowing the simultaneous identification of targets spanning a wide size range, from short microRNAs ...
Yunxuan Li +12 more
wiley +1 more source
An Immersive P300 Brain-Computer Interface Based on 3D Morphological Stimuli and Self-Adaptive Bayesian Linear Discriminant Analysis. [PDF]
Biomimetics (Basel)Luo J +8 more
europepmc +1 more source
Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors
Advanced Science, EarlyView.This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng +12 more
wiley +1 more source
Sample Size Recalculation in Adaptive Group Sequential Study Designs for Comparing Restricted Mean Survival Times. [PDF]
Stat MedHerrmann C, Blanche P.
europepmc +1 more source
Advanced Science, EarlyView.Current technologies for spinal cord optogenetic stimulation rely on external power sources and face reliability constraints in freely behaving animals. Here, a fully implantable, battery‐powered optoelectronic device is introduced, enabling operation in any selected environment with wireless recharging for months‐long stimulation.
Shahriar Shalileh +8 more
wiley +1 more source
Two-dimensional ETTC-labeled longitudinal and lateral conflicts for interpretable real-time crash risk prediction in freeway interchange diverging areas. [PDF]
PLoS OneTang F, Wu R, Liu Z, Zhong S.
europepmc +1 more source
Advanced Science, EarlyView.NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang +12 more
wiley +1 more source