Floral meristem (FM) activity is crucial for the initiation of floral organs. In this study, SE represses IPT7 expression and cytokinin signaling via both the miR171c‐5p–KNAT2 and miR164c–CUC1/2–KNAT2 regulatory modules, thereby repressing FM activity. In contrast, STM induces both KNAT2 and IPT7 expression.
Wen Yang +11 more
wiley +1 more source
Air quality index prediction using a hybrid CEEMDAN-CNN-IGWO-BiGRU-Attention model. [PDF]
Fang Y, Liu S, Su Z.
europepmc +1 more source
CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma +12 more
wiley +1 more source
A Robust Deep Learning Approach for COPD Automated Detection. [PDF]
Xu S +5 more
europepmc +1 more source
Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
Triad-LMF: a hierarchical low-rank multimodal fusion framework for robust cancer subtype classification using multi-omics data. [PDF]
Tan X +6 more
europepmc +1 more source
Decision on Optimal Combinatorial Therapies in Immune-mediated inflammatory diseases using Systems approaches (DocTIS): protocol for a single-arm, adaptive basket trial in rheumatoid and psoriatic arthritis. [PDF]
Sheppard R +7 more
europepmc +1 more source
A hybrid CNN-XLSTM-GRU deep learning model with autoencoder-based feature selection for hypothyroidism diagnosis. [PDF]
Kesavulu D, R K.
europepmc +1 more source
Robust Pose and Inertial Parameter Estimation of an Unknown Aircraft Based on Variational Bayesian Dual Vector Quaternion Extended Kalman Filter. [PDF]
Xu S, Fang Y, Huang H.
europepmc +1 more source
A novel federated learning framework for medical imaging: Resource-efficient approach combining PCA with early stopping. [PDF]
Nanekaran NP, Ukwatta E.
europepmc +1 more source

