Results 101 to 110 of about 7,890,396 (298)
The optimal prize structure of symmetric Tullock contests [PDF]
, 2008 We show that the optimal prize structure of symmetric n-player Tullock tournaments assigns the entire prize pool to the winner, provided that a symmetric pure strategy equilibrium exists.
Segev, Ella, Schweinzer, Paul
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The Optimal Solution under Cumulative Prospect Theory
, 2012 [[abstract]]A fundamental problem in the financial mathematics is to find out an optimal strategy for the investment. And the most used setting to discuss the optimal investment is the expected utility optimization.
Wang, Li-Sen, 王立森
core
A Distributed Q Learning Spectrum Decision Scheme for Cognitive Radio Sensor Network
International Journal of Distributed Sensor Networks, 2015 Cognitive spectrum management can improve the utilization efficiency of spectrum while increasing the energy consumption of sensor network nodes. Hence, how to balance the energy consumption and spectrum efficiency has become a critical challenge in the ...
Jian He +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
An evolutionary game based security decision algorithm for wireless sensor networks
Journal of Measurement Science and Instrumentation, 2022 When using traditional game methods to study information security of the wireless sensor networks, players are mostly based on the assumption of completely rational.
XIA Jinzong +3 more
doaj
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Optimal asset allocation for aggregated defined benefit pension funds with stochastic interest rates [PDF]
, 2008 In this paper we study the optimal management of an aggregated pension fund of defined benefit type, in the presence of a stochastic interest rate. We suppose that the sponsor can invest in a savings account, in a risky stock and in a bond, with the ...
Rincón-Zapatero, Juan Pablo +1 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source