Results 121 to 130 of about 7,890,396 (298)

National Community Health Digitization Strategy 2020-2025

open access: yes, 2020
Despite its importance, the delivery of community health continues to suffer from weak data collection and reporting tools. This hinders the optimal use of community-level data to inform public health response and resource allocation.

core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Age dependent investing: Optimal funding and investment strategies in defined contribution pension plans when members are rational life cycle financial planners [PDF]

open access: yes
A defined contribution pension plan allows consumption to be redistributed from the plan member’s working life to retirement in a manner that is consistent with the member’s personal preferences.
Zhang, Yumeng   +2 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Bayesian Portfolio Selection with Gaussian Mixture Returns [PDF]

open access: yes
Markowitz portfolio selection is challenged by huge implementation barriers. This paper addresses the parameter uncertainty and deviation from normality in a Bayesian framework. The non-normal asset returns are modeled as finite Gaussian mixtures.
Qian, Hang
core  

A comparison of design and model selection methods for supersaturated experiments

open access: yes
Various design and model selection methods are available for supersatu-rated designs having more factors than runs but little research is available ontheir comparison and evaluation.
Woods, David C., Marley, Christopher J.
core   +1 more source

Selection of optimal strategy for managing decentralized solar PV systems considering uncertain weather conditions

open access: yesScientific Reports
Solar power is a promising source of energy that is environmentally friendly, sustainable, and renewable. Solar photovoltaic (PV) panels are the most common and mature technology used to harness solar energy. Unfortunately, these panels are prone to dust
Assia Chadly   +5 more
doaj   +1 more source

Optimal selection strategy of surface-to-air anti-missile kill chain based on mixed swarm evolutionary meta-game

open access: yesZhongguo Jianchuan Yanjiu
ObjectiveTo optimize the kill chain design process and enhance combat capabilities, this study investigates a kill chain optimization algorithm based on a hybrid swarm evolutionary meta-game.
Bowen LI   +6 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Deep reinforcement learning for network resource optimization in MIMO-NOMA networks to maximize utilization with minimal overhead

open access: yesScientific Reports
The next-generation multiple-input Multiple-Output Non-Orthogonal Medium Access (MIMO-NOMA) system requires seamless mobility, enhanced spectral efficiency, and higher sum rates with minimal interference.
Hassan Fareed M Lahza   +6 more
doaj   +1 more source

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