Results 91 to 100 of about 5,276,757 (246)
Optimal Operation of a Wind Driven System
Journal of King Saud University: Engineering Sciences, 2004 This paper presents a number of controlling techniques that can used in extracting the wind energy from a wind prime mover. The extraction of wind energy bears in mind the target of matching the electric power needed by an electric generator with the ...
Maamar Taleb
doaj +1 more source
Conserved quantities, optimal system and explicit solutions of a (1 + 1)-dimensional generalised coupled mKdV-type system. [PDF]
J Adv Res, 2021 Khalique CM, Simbanefayi I.
europepmc +1 more source
Analysis of dynamic traffic models and assignments [PDF]
, 2007 This paper develops a comprehensive framework for analysing and solving traffic models and assignments in dynamic setting. Traffic models capture the time-varying travel times and flows on a road network and traffic assignments represent the ...
Chow, A.H.F.
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Optimal System and Group Invariant Solutions of the Whitham-Broer-Kaup System
Advances in Mathematical Physics, 2019 From the nonlocal symmetries of the Whitham-Broer-Kaup system, an eight-dimensional Lie algebra is found and the corresponding one-dimensional optimal system is constructed to provide an inequivalent classification.
Xiaorui Hu, Yongyang Jin, Kai Zhou
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Time-optimal controlonasubspaceforthetwoand three-dimensional system
Visnik Harkivsʹkogo Nacionalʹnogo Universitetu im. V.N. Karazina. Cepiâ Matematika, Prikladna Matematika i MehanikaThis article is devoted to the problem of the optimal synthesis on a subspace for the 2 and 3-dimensional case for the linear control system $\dot{x_1} = u, \dot{x}_i=x_{i-1}, i=\overline{2,n}$ with $|u|\le1$.
Oleh Vozniak, Valery Korobov
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
OPTIMAL ENERGY SYSTEM DESIGN UNDER UNCERTAIN PARAMETERS
Chemical Engineering Transactions, 2009 preview not available - see full-text PDF article.
M. Dubuis, F. Marechal
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