Results 91 to 100 of about 21,981,955 (264)
Optimal Taxation and Optimal Tax Systems [PDF]
The theory of optimal taxation has , for the pas two decades , been the reigning normative approach of taxation. This paper argues that , in its current state, optimal tax theory is incomplete as a guide to action concerning many critical issues in tax ...
Joel Slemrod
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Optimal System and Group Invariant Solutions of the Whitham-Broer-Kaup System
From the nonlocal symmetries of the Whitham-Broer-Kaup system, an eight-dimensional Lie algebra is found and the corresponding one-dimensional optimal system is constructed to provide an inequivalent classification.
Xiaorui Hu, Yongyang Jin, Kai Zhou
doaj +1 more source
Conserved quantities, optimal system and explicit solutions of a (1 + 1)-dimensional generalised coupled mKdV-type system. [PDF]
Khalique CM, Simbanefayi I.
europepmc +1 more source
Power system stabilizer (PSS) is one of the most important controllers in modern power systems for damping low frequency oscillations. Many efforts have been dedicated to design the tuning methodologies and allocation techniques to obtain optimal damping
K.P. Wong +7 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Time-optimal controlonasubspaceforthetwoand three-dimensional system
This article is devoted to the problem of the optimal synthesis on a subspace for the 2 and 3-dimensional case for the linear control system $\dot{x_1} = u, \dot{x}_i=x_{i-1}, i=\overline{2,n}$ with $|u|\le1$.
Oleh Vozniak, Valery Korobov
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Multi-phase Homing Optimal Control for Parafoil System
In this paper an optimal control method for parafoil system homing planning is introduced, which includes multi-phase homing arrangement, optimal homing path calculation using genetic algorithm(GA), and Bezier curves based path planning for parafoil ...
Gu F(谷丰) +3 more
core
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

