Results 81 to 90 of about 1,790,404 (269)

Optimal system and dynamics of optical soliton solutions for the Schamel KdV equation. [PDF]

Sci Rep, 2023
Hussain A, Chahlaoui Y, Usman M, Zaman FD, Park C.   +4 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Sensitivity improved Cerenkov luminescence endoscopy using optimal system parameters. [PDF]

Quant Imaging Med Surg, 2022
Chen X, Wang X, Yan T, Zheng Y, Cao H, Ren F, Cao X, Meng X, Lu X, Liang S, Wu K.   +10 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Optimal Operation of a Wind Driven System

Journal of King Saud University: Engineering Sciences, 2004
This paper presents a number of controlling techniques that can used in extracting the wind energy from a wind prime mover. The extraction of wind energy bears in mind the target of matching the electric power needed by an electric generator with the ...
Maamar Taleb
doaj   +1 more source

Conserved quantities, optimal system and explicit solutions of a (1 + 1)-dimensional generalised coupled mKdV-type system. [PDF]

J Adv Res, 2021
Khalique CM, Simbanefayi I.
europepmc   +1 more source

Optimal control of overdamped systems

Physical Review E, 2015
Nonequilibrium physics encompasses a broad range of natural and synthetic small-scale systems. Optimizing transitions of such systems will be crucial for the development of nanoscale technologies and may reveal the physical principles underlying biological processes at the molecular level.
Zulkowski, Patrick R., DeWeese, Michael R.   +1 more
openaire   +4 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Time-optimal controlonasubspaceforthetwoand three-dimensional system

Visnik Harkivsʹkogo Nacionalʹnogo Universitetu im. V.N. Karazina. Cepiâ Matematika, Prikladna Matematika i Mehanika
This article is devoted to the problem of the optimal synthesis on a subspace for the 2 and 3-dimensional case for the linear control system $\dot{x_1} = u, \dot{x}_i=x_{i-1}, i=\overline{2,n}$ with $|u|\le1$.
Oleh Vozniak, Valery Korobov
doaj   +1 more source

Optimal System and Group Invariant Solutions of the Whitham-Broer-Kaup System

Advances in Mathematical Physics, 2019
From the nonlocal symmetries of the Whitham-Broer-Kaup system, an eight-dimensional Lie algebra is found and the corresponding one-dimensional optimal system is constructed to provide an inequivalent classification.
Xiaorui Hu, Yongyang Jin, Kai Zhou
doaj   +1 more source