Results 51 to 60 of about 5,025,116 (269)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Constructing the optimal experimental autoimmune thyroiditis mouse model using porcine thyroglobulin

open access: yesFrontiers in Immunology
IntroductionAutoimmune thyroiditis (AIT) is a chronic autoimmune disease characterized by lymphocytic infiltration of the thyroid gland and elevated specific antibodies.
Ke Liu   +8 more
doaj   +1 more source

Effect of adsorption of surfactant mixtures on wettability of sintering dust [PDF]

open access: yesJournal of Mining and Metallurgy. Section B: Metallurgy
In order to improve the wettability of sintering dust, we investigated the action mechanism of Triton X-100 (TX-100), which synergizes with Dodecyl Trimethyl Ammonium Bromide (DTAB). The settling times of nine different types of surfactants were measured,
Ju J.-T., Wei L.-L., Bi Q., Hu Y.-W.
doaj   +1 more source

Optimal selection of sampling filter membranes for alpha radioactive aerosols based on spectrum tailing and detection efficiency tests

open access: yesHe jishu, 2021
BackgroundSampling filter membrane is an important part of the continuous monitoring system for radioactive aerosols. The performance of the sampling filter membrane directly affects detection efficiency of the system. In addition, tailing effect in α spectra increases the difficulty of identifying nuclides, reduces the accuracy of aerosol measurement,
ZHANG Junxin   +4 more
openaire   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Aeroacoustic analysis of main rotor and tail rotor interaction [PDF]

open access: yes, 2008
The increased restrictions placed on helicopter noise levels over recent decades have encouraged manufacturers to better understand tail rotor noise and its aerodynamic sources.
Fletcher, Timothy M.   +5 more
core   +6 more sources

Tail Risk Constraints and Maximum Entropy

open access: yesEntropy, 2015
Portfolio selection in the financial literature has essentially been analyzed under two central assumptions: full knowledge of the joint probability distribution of the returns of the securities that will comprise the target portfolio; and investors ...
Donald Geman   +2 more
doaj   +1 more source

Characteristics of biter and victim piglets apparent before a tail biting outbreak [PDF]

open access: yes, 2011
Little is known about the characteristics of biters and victims before the appearance of a tail-biting outbreak in groups of pigs. This study aimed to characterise biters and victims (according to gender and performance) and to quantify their behavioural
Kemp, B.   +5 more
core   +1 more source

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