Results 71 to 80 of about 5,025,116 (269)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

From phenotype to receptor: validating physiological clustering of Escherichia coli phages through comprehensive receptor analysis

open access: yesJournal of Virology
Understanding the relationship between bacteriophage (phage) classification and target receptors is crucial for phage ecology and applied research.
Tomoyoshi Kaneko   +5 more
doaj   +1 more source

Numerical Simulation of an Oscillatory-Type Tidal Current Powered Generator Based on Robotic Fish Technology

open access: yesApplied Sciences, 2017
The generation of clean renewable energy is becoming increasingly critical, as pollution and global warming threaten the environment in which we live.
Ikuo Yamamoto   +3 more
doaj   +1 more source

Comonotonic approximations for optimal portfolio selection problems. [PDF]

open access: yes
We investigate multiperiod portfolio selection problems in a Black & Scholes type market where a basket of 1 riskless and m risky securities are traded continuously.
Kaas, R   +4 more
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

USE OF GRADATION CORRECTION METHOD FOR IMPROVING THE VISUALIZATION OF COMPUTED TOMOGRAPHY RESULTS

open access: yesКомпютерні системи та інформаційні технології
The aim of this work is to enhance the quality of visualization of computed tomography (CT) results by improving digital image processing methods, particularly through the use of the gradation correction (GC).
Євген ВАКУЛІК   +1 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

THE CONCEPT OF THE COEFFICIENT OF ELLIPTIC TRAPEZOID WING AND THE METHOD OF ITS ASSESSMENT

open access: yesАвіаційно-космічна техніка та технологія, 2019
When developing modifications of the transport category aircraft to increase their transport efficiency and economy in many cases, there is a need for profound changes in wing parameters.
Александр Васильевич Лось   +1 more
doaj   +1 more source

Optimized Selective Harmonic Elimination in CHB-MLI Using Red-Tailed Hawk Algorithm for Unequal DC Sources

open access: yesInternational Journal of Robotics and Control Systems
The study develops an optimized SHE procedure to regulate a CHB-MLI powered by PV modules which use unequal DC sources. The main goal involves finding suitable switching angles that produce minimal low-order harmonics during steady output voltage operation under variable input scenarios.
Elaf Hamzah Yahia   +7 more
openaire   +1 more source

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