Results 91 to 100 of about 5,025,116 (269)

Thyroid cancer imaging in vivo by targeting the anti-apoptotic molecule galectin-3.

open access: yesPLoS ONE, 2008
BackgroundThe prevalence of thyroid nodules increases with age, average 4-7% for the U.S.A. adult population, but it is much higher (19-67%) when sub-clinical nodules are considered.
Armando Bartolazzi   +11 more
doaj   +1 more source

Saddlepoint Approximations for Optimal Unit Root Tests [PDF]

open access: yes
This paper provides a (saddlepoint) tail probability approximation for the distribution of an optimal unit root test. Under restrictive assumptions, Gaussianity and known covariance structure, the order of error of the approximation is given.
Patrick Marsh
core  

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Regional modeling of zero-inflated precipitation in Pakistan by classical and Bayesian approaches

open access: yesJournal of Hydrology: Regional Studies
Study region: Pakistan exhibits pronounced spatial and seasonal variability in rainfall patterns, with extreme precipitation posing major challenges for flood risk management, agriculture, and infrastructure planning. Accurate estimation of return levels
Aamar Abbas, Touqeer Ahmad, Ishfaq Ahmad
doaj   +1 more source

Manufacture of IRDye800CW-coupled Fe3O4 nanoparticles and their applications in cell labeling and in vivo imaging

open access: yesJournal of Nanobiotechnology, 2010
Background In recent years, near-infrared fluorescence (NIRF)-labeled iron nanoparticles have been synthesized and applied in a number of applications, including the labeling of human cells for monitoring the engraftment process, imaging tumors ...
Chen Zhongping   +4 more
doaj   +1 more source

Time variation in the tail behaviour of bunds futures returns [PDF]

open access: yes
The present paper focuses on three questions: (i) Are heavy tails a relevant feature of the distribution of BUND futures returns? (ii) Is the tail behaviour constant over time?
Upper, Christian, Werner, Thomas
core  

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Development of a cascade recognition method for short-term heavy precipitation over the Yangtze River Delta

open access: yesFrontiers in Environmental Science
Three key challenges hinder the identification of short-term heavy precipitation (STHP) over the Yangtze River Delta region: feature selection, sample imbalance, and poor physical performance of models.
Jingjing An   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy