Results 81 to 90 of about 5,025,116 (269)

Looking ahead in extension work in Otter Tail County

open access: yes, 1958
75 pages; includes charts, illustrations, maps and photographThis archival publication may not reflect current scientific knowledge or recommendations.
Long Range Planning Committees   +1 more
core  

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Machine learning model for diagnosing salivary gland adenoid cystic carcinoma based on clinical and ultrasound features

open access: yesInsights into Imaging
Objective To develop and validate machine learning (ML) models for diagnosing salivary gland adenoid cystic carcinoma (ACC) in the salivary glands based on clinical and ultrasound features.
Huan-Zhong Su   +6 more
doaj   +1 more source

Effect of Alkyl Chain Length on Physicochemical and Pharmacokinetic Performance of Aripiprazole Fatty Acid Prodrugs for Long-Acting Injectable Suspensions

open access: yesPharmaceutics
Background/Objectives: Long-acting injectable aqueous suspensions based on fatty acid prodrugs offer a compelling strategy for chronic disease management. However, the selection of optimal alkyl chain length remains largely empirical, as its influence on
An Chen   +5 more
doaj   +1 more source

Unbiased Tail Estimation by an Extension of the Generalized Pareto Distribution [PDF]

open access: yes
AMS classifications: 62G20; 62G32;bias;exchange rate;heavy tails;peaks-over-threshold;regular variation;tail ...
Segers, J., Beirlant, J., Joossens, E.
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Morphological, lytic, and genetic characteristics of three Brucella phages isolated from Inner Mongolia Autonomous Region

open access: yesFrontiers in Microbiology
This study comprehensively examined three Brucella phages (A1, NMY-1, and NMY-2) isolated from Inner Mongolia Autonomous Region. Electron microscopy classified them as short-tailed phages.
Yu Zhang   +9 more
doaj   +1 more source

Induced Partitioning for Incremental Feature Selection via Rough Set Theory and Long-tail Position Grey Wolf Optimizer

open access: yesActa Informatica Pragensia
Background: Feature selection methods play a crucial role in handling challenges such as imbalanced classes, noisy data and high dimensionality. However, existing techniques, including swarm intelligence and set theory approaches, often struggle with high-dimensional datasets due to repeated reassessment of feature selection, leading to increased ...
Said Al Afghani Edsa, Khamron Sunat
openaire   +2 more sources

Assessing Confidence Intervals for the Tail Index by Edgeworth Expansions for the Hill Estimator [PDF]

open access: yes
AMS classifications: 62G20, 62G32;asymptotic normality;confidence intervals;Edgeworth expansions;extreme value index;Hill estimator;regular variation;tail ...
Segers, J., Haeusler, E.
core  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

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