Results 121 to 130 of about 6,516 (216)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Hybrid Wasserstein Distance: An Approximation for Optimal Transport Distances

open access: yesComputation
Projection-based variants of optimal transport, such as the Sliced Wasserstein (SW) and its extensions, have become popular alternatives to classical Wasserstein distances due to their scalability and analytical tractability.
Sara Nassar   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A Mathematical Framework for Modeling Global Value Chain Networks

open access: yesFoundations
Global value chains (GVCs) have evolved into highly interconnected and geographically fragmented production networks, increasing exposure to systemic disruptions and revealing the limitations of static input–output and conventional network approaches ...
Georgios Angelidis
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Dual-Graph Multimodal Named Entity Recognition With Optimal Transport Fusion

open access: yesIEEE Access
Multimodal Named Entity Recognition (MNER) aims to leverage both textual and visual information to perform entity recognition and classification tasks collaboratively, holding significant application value in scenarios such as social media.
Shihong Wu, Yupeng Ma, Ming Zhang
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Multi-Scale Optimal Transport Transformer for Efficient Exemplar-Based Image Translation

open access: yesBig Data and Cognitive Computing
Exemplar-based image translation generates an output image by transferring appearance from a reference exemplar to a content image. Existing works only consider the local correspondences between two modalities, and ignore the global distributions in each
Jinsong Zhang, Xiongzheng Li, Yuqin Lin
doaj   +1 more source

The McCormick Martingale Optimal Transport

open access: yesSIAM Journal on Financial Mathematics
36 pages, final ...
Erhan Bayraktar   +2 more
openaire   +2 more sources

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