Results 71 to 80 of about 90,500 (318)
Measuring the Optimality of Hadoop Optimization
CoRR, 2013 In recent years, much research has focused on how to optimize Hadoop jobs. Their approaches are diverse, ranging from improving HDFS and Hadoop job scheduler to optimizing parameters in Hadoop configurations. Despite their success in improving the performance of Hadoop jobs, however, very little is known about the limit of their optimization ...
Woo-Cheol Kim +2 more
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Free-energy Minimization and The Dark Room Problem
Frontiers in Psychology, 2012 Recent years have seen the emergence of an important new fundamental theory of brain function. This theory brings information-theoretic, Bayesian, neuroscientific, and machine learning approaches into a single framework whose overarching principle is the
Karl eFriston +2 more
doaj +1 more source
An Optimal Preparation for Studying Optimization [PDF]
Neuron, 2000 Imagine a fly navigating through a forest at 2 m/s. In order to correct for the effects of the wind and other flight instabilities, the fly must continually estimate its heading direction if only to avoid running into a tree or inadvertently flying in circles. Given the striking prominence of eyes on a fly's body, it is not surprising that vision plays
openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
, 1995 In this paper, we propose to start addressing the issues outlined above from the perspective of Optimality Theory (OT, Prince and Smolensky, 1993) and test the hypothesis that different patterns of extractability across languages result from different ...
Raymond, William +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Quality of drinking water and health of population in the Republic of Altai
Бюллетень сибирской медицины, 2009 The influence of the chemical composition of water in the Republic of Altai (RA) on medical-demographic indices has been studied. It has been found that the water is poorly mineralized, the fluorine content in it is three times lower than the optimal one,
T. V. Yarkina, L. P. Volkotrub
doaj +1 more source
Optimality in robot motion [PDF]
Communications of the ACM, 2014 Exploring the distinction between an optimal robot motion and a robot motion resulting from the application of optimization techniques.
Laumond, Jean-Paul +2 more
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source