Results 131 to 140 of about 2,373,071 (323)
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Volume staging for arteriovenous malformation SRS treatment using VMAT
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Volume staging involves dividing the target volume into smaller parts and treating each part separately. In this study, the feasibility of volume‐staged stereotactic radiosurgery (VS‐SRS) on a linear accelerator using volumetric modulated arc therapy (VMAT) and a frameless patient positioning system is investigated.
Claudia Mendez, Ermias Gete
wiley +1 more source
ePyDGGA: automatic configuration for fitting epidemic curves
Scientific ReportsMany epidemiological models and algorithms are used to fit the parameters of a given epidemic curve. On many occasions, fitting algorithms are interleaved with the actual epidemic models, which yields combinations of model-parameters that are hard to ...
Josep Alòs +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract This study aimed to evaluate the clinical beam commissioning results and lateral penumbra characteristics of our new pencil beam scanning (PBS) proton therapy using a multi‐leaf collimator (MLC) calculated by use of a commercial Monte Carlo dose engine.
Yuki Tominaga +5 more
wiley +1 more source
Cultural Sociology, 2011 Drawing on material from a broad range of fields, this article identifies an ‘optimism of everyday life’ and proposes that it performs significant psychological, social and cultural functions. These functions are briefly reviewed, with particular reference to psychological and physical health, family and social relationships and the achievement of ...
openaire +3 more sources
Journal of Modern Power Systems and Clean Energy, 2018 Distributed photovoltaic generators (DPGs) have been integrated into the medium/low voltage distribution network widely. Due to the randomness and fluctuation of DPG, however, the distribution and direction of power flow are changed frequently on some ...
Bin LI +3 more
doaj +1 more source
Combinations and Mixtures of Optimal Policies in Unichain Markov Decision Processes are Optimal [PDF]
arXiv, 2005 We show that combinations of optimal (stationary) policies in unichain Markov decision processes are optimal. That is, let M be a unichain Markov decision process with state space S, action space A and policies \pi_j^*: S -> A (1\leq j\leq n) with optimal average infinite horizon reward.
arxiv
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source