Results 121 to 130 of about 2,429,878 (317)
Empipe3D™ User’s Manual Version 4.0 -- UNIX
, 1997 Empipe3D is a powerful and friendly software system for automated electromagnetic (EM) design optimization, driving the 3D field solvers Ansoft HFSS and HP HFSS.
Bandler, John W. +3 more
core
Scientific ReportsUtilization of optimization technique is a must in the design of contemporary antenna systems. Often, global search methods are necessary, which are associated with high computational costs when conducted at the level of full-wave electromagnetic (EM ...
Slawomir Koziel +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
OSA90/hope™ User’s Manual Version 4.0 -- UNIX
, 1997 OSA90/hope is a general CAD software system offering simulation, modeling, statistical analysis, nominal and yield optimization, and data visualization for linear and nonlinear analog circuits. Its open architecture allows you to create fully optimizable
Bandler, John W. +3 more
core
JayaX: Jaya algorithm with xor operator for binary optimization
, 2019 Jaya is a population-based heuristic optimization algorithm proposed for solving constrained and unconstrained optimization problems. The peculiar distinct feature of Jaya from the other population-based algorithms is that it updates the positions of ...
Aslan, Murat +2 more
core +1 more source
Multi-Objective Optimization Technique Based on QUBO and an Ising Machine
IEEE AccessWith an increase in the complexity of society, solving multi-objective optimization problems (MOPs) has become crucial. In this study, we introduced a novel method called “quadratic unconstrained binary optimization based on the weighted normal ...
Hiroshi Ikeda, Takashi Yamazaki
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source