Results 51 to 60 of about 5,593,327 (347)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Detecting and generating overlapping nested communities

open access: yesApplied Network Science, 2023
Nestedness has been observed in a variety of networks but has been primarily viewed in the context of bipartite networks. Numerous metrics quantify nestedness and some clustering methods identify fully nested parts of graphs, but all with similar ...
Imre Gera, András London
doaj   +1 more source

Some notes on continuity in convex optimization [PDF]

open access: yesarXiv, 2021
We provide proof that the optimal value function of a convex parametrized optimization problem in Euclidean spaces is itself a convex function onto the extended real line.
arxiv  

Speed trajectory planning at signalized intersections using sequential convex optimization

open access: yes, 2018
An algorithm is developed to optimize vehicle speed trajectory over multiple signalized intersections with known traffic signal information to minimize fuel consumption and travel time, and to meet ride comfort requirements using sequential convex ...
de nunzio   +7 more
core   +1 more source

Scalarizing Functions in Bayesian Multiobjective Optimization [PDF]

open access: yes, 2019
Scalarizing functions have been widely used to convert a multiobjective optimization problem into a single objective optimization problem. However, their use in solving (computationally) expensive multi- and many-objective optimization problems in ...
Chugh, Tinkle
core   +2 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Computationally-efficient statistical design and yield optimization of resonator-based notch filters using feature-based surrogates

open access: yesScientific Reports, 2023
Modern microwave devices are designed to fulfill stringent requirements pertaining to electrical performance, which requires, among others, a meticulous tuning of their geometry parameters.
Slawomir Koziel, Tanveerul Haq
doaj   +1 more source

Development of an Ant Colony Optimization Algorithm to improve Maintenance Process Efficiency [PDF]

open access: yes, 2010
Efficient maintenance policies are of fundamental importance because of their fallbacks into the safety and economics of air traffic operations. Usually the optimization of maintenance process is limited to a resource optimization in position and number.
D'AMATO, EGIDIO   +2 more
core  

Novel Artificial Human Optimization Field Algorithms - The Beginning

open access: yes, 2019
New Artificial Human Optimization (AHO) Field Algorithms can be created from scratch or by adding the concept of Artificial Humans into other existing Optimization Algorithms.
Gajawada, Satish, Mustafa, Hassan
core   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

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