Results 61 to 70 of about 5,593,327 (347)

Optimization and Optimal Control [PDF]

, 2003
Extragradient Approach to the Solution of Two Person Non-Zero Sum Games (A Antipin) Nonlinear Phenomena in Economics (S Budnyam) On Some Theory, Methods and Algorithms for Concave Programming (R Enkhbat) Maximum Clique Regularizations (D Fortin & I Tseveendorj) The Role of Optimization in Economics (D W Katzner) A Global Optimization Approach to ...
Rentsen Enkhbat, Panos M. Pardalos, Ider Tseveendorj   +2 more
openaire   +2 more sources

Optimal Solvers for PDE-Constrained Optimization [PDF]

SIAM Journal on Scientific Computing, 2010
Optimization problems with constraints which require the solution of a partial differential equation arise widely in many areas of the sciences and engineering, in particular in problems of design. The solution of such PDE-constrained optimization problems is usually a major computational task.
Rees, Tyrone, Thorne, HS, Wathen, AJ
openaire   +4 more sources

Constraining continuous topology optimizations to discrete solutions for photonic applications [PDF]

arXiv, 2021
Photonic topology optimization is a technique used to find the electric permittivity distribution of a device that optimizes an electromagnetic figure-of-merit. Two common techniques are used: continuous density-based optimizations that optimize a grey-scale permittivity defined over a grid, and discrete level-set optimizations that optimize the shape ...
arxiv  

Oracle-Based Robust Optimization via Online Learning [PDF]

, 2014
Robust optimization is a common framework in optimization under uncertainty when the problem parameters are not known, but it is rather known that the parameters belong to some given uncertainty set.
Ben-Tal, Aharon, Hazan, Elad, Koren, Tomer, Mannor, Shie   +3 more
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Determinants of implementation of continuous glucose monitoring for patients with Insulin-Treated type 2 diabetes: a national survey of primary care providers

BMC Primary Care
Objectives To identify determinants of continuous glucose monitoring (CGM) implementation from primary care providers’ (PCPs’) perspectives and examine the associations of these determinants with both PCP intent to discuss CGM with eligible patients and ...
Varsha G. Vimalananda, Ben Kragen, Alison J. Leibowitz, Shirley Qian, Jolie Wormwood, Amy M. Linsky, Patricia Underwood, Paul R. Conlin, Bo Kim   +8 more
doaj   +1 more source

Quality and Computation Time in Optimization Problems [PDF]

arXiv, 2021
Optimization problems are crucial in artificial intelligence. Optimization algorithms are generally used to adjust the performance of artificial intelligence models to minimize the error of mapping inputs to outputs. Current evaluation methods on optimization algorithms generally consider the performance in terms of quality.
arxiv  

Taguchi Optimization Method for Identifying Surface Roughness [PDF]

, 2011
Disain parameter Taguchi adalah satu perangkat yang sangat penting untuk mendapatkan disain yang bersifat leibh akurat. Disain Taguchi menawarkan satu pendekatan yang sederhana dan sistematik untuk optimisasi prestasi, kualitas dan biaya operasi. Tujuan
Zaid, M. (Mohamad)
core  

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Optimal Gaps in Optimal Paradigms

Catalan Journal of Linguistics, 2005
This article develops a treatment of phonologically motivated gaps in paradigms within Optimal Paradigms Theory (McCarthy 2001). The gaps are instances of absolute ungrammaticality, i.e. situations in which there is no output for a given input. In the approach developed here, gaps arise when phonological markedness constraints outrank constraints ...
openaire   +6 more sources