Results 61 to 70 of about 9,630,828 (353)
Detecting and generating overlapping nested communities
Applied Network Science, 2023 Nestedness has been observed in a variety of networks but has been primarily viewed in the context of bipartite networks. Numerous metrics quantify nestedness and some clustering methods identify fully nested parts of graphs, but all with similar ...
Imre Gera, András London
doaj +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
, 2018 Theoretical and empirical research on evolutionary computation methods complement each other by providing two fundamentally different approaches towards a better understanding of black-box optimization heuristics.
Badkobeh Golnaz +5 more
core +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Complex & Intelligent Systems, 2023 Designing reasonable architectures of convolutional neural network (CNN) for specific image segmentation remains a challenging task, as the determination of the structure and hyperparameters of CNN depends heavily on expertise and requires a great deal ...
Wei Wang, Xianpeng Wang, Xiangman Song
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Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
, 2018 Optimization over non-negative polynomials is fundamental for nonlinear systems analysis and control. We investigate the relation between three tractable relaxations for optimizing over sparse non-negative polynomials: sparse sum-of-squares (SSOS ...
Fantuzzi, Giovanni +2 more
core +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Progressive construction of a parametric reduced-order model for PDE-constrained optimization [PDF]
, 2014 An adaptive approach to using reduced-order models as surrogates in PDE-constrained optimization is introduced that breaks the traditional offline-online framework of model order reduction.
Farhat, Charbel, Zahr, Matthew J.
core
BMC Primary CareObjectives To identify determinants of continuous glucose monitoring (CGM) implementation from primary care providers’ (PCPs’) perspectives and examine the associations of these determinants with both PCP intent to discuss CGM with eligible patients and ...
Varsha G. Vimalananda +8 more
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