Results 61 to 70 of about 6,440,759 (285)

Equating κ Maximum Degrees in Graphs without Short Cycles

open access: yesDiscussiones Mathematicae Graph Theory, 2020
For an integer k at least 2, and a graph G, let fk(G) be the minimum cardinality of a set X of vertices of G such that G − X has either k vertices of maximum degree or order less than k.
Fürst Maximilian   +4 more
doaj   +1 more source

Low-cost quasi-global optimization of expensive electromagnetic simulation models by inverse surrogates and response features

open access: yesScientific Reports, 2022
Conceptual design of contemporary high-frequency structures is typically followed by a careful tuning of their parameters, predominantly the geometry ones. The process aims at improving the relevant performance figures, and may be quite expensive.
Slawomir Koziel   +1 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Normalization for FDS of Transformer Insulation Considering the Synergistic Effect Generated by Temperature and Moisture

open access: yesIEEE Access, 2020
Frequency domain spectroscopy (FDS) technique is widely applied in the condition assessment of the oil-paper system in power transformers. However, the synergistic effect generated by moisture and temperature on the FDS data cannot be analyzed by the ...
Xianhao Fan   +5 more
doaj   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Using Big Data-machine learning models for diabetes prediction and flight delays analytics

open access: yesJournal of Big Data, 2020
Introduction Nowadays large data volumes are daily generated at a high rate. Data from health system, social network, financial, government, marketing, bank transactions as well as the censors and smart devices are increasing.
Thérence Nibareke, Jalal Laassiri
doaj   +1 more source

A new approach exploiting thermally activated delayed fluorescence molecules to optimize solar thermal energy storage [PDF]

open access: gold, 2022
Fan‐Yi Meng   +8 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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