Results 81 to 90 of about 10,333,076 (321)
Sparsity-Aware Adaptive Algorithms Based on Alternating Optimization with Shrinkage
, 2014 This letter proposes a novel sparsity-aware adaptive filtering scheme and algorithms based on an alternating optimization strategy with shrinkage.
de Lamare, Rodrigo C. +1 more
core +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Polynomial Optimization with Applications to Stability Analysis and Control - Alternatives to Sum of Squares [PDF]
, 2015 In this paper, we explore the merits of various algorithms for polynomial optimization problems, focusing on alternatives to sum of squares programming.
Kamyar, Reza, Peet, Matthew
core
IEEE Access, 2019 In this paper, a simulation model describing the operation of a PV/wind/diesel hybrid microgrid system with battery bank storage has been proposed. Optimal sizing of the proposed system has been presented to minimize the cost of energy (COE) supplied by ...
A. Diab +4 more
semanticscholar +1 more source
Optimizing the quantum adiabatic algorithm [PDF]
Physical Review A, 2016 8 pages, 9 ...
Hu, Hongye, Wu, Biao
openaire +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Resilient Distributed Optimization Algorithms for Resource Allocation [PDF]
, 2019 Distributed algorithms provide flexibility over centralized algorithms for resource allocation problems, e.g., cyber-physical systems. However, the distributed nature of these algorithms often makes the systems susceptible to man-in-the-middle attacks ...
Alizadeh, Mahnoosh +2 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source