Results 61 to 70 of about 10,333,076 (321)

Optimized K‐Means Algorithm [PDF]

open access: yesMathematical Problems in Engineering, 2014
The localization of the region of interest (ROI), which contains the face, is the first step in any automatic recognition system, which is a special case of the face detection. However, face localization from input image is a challenging task due to possible variations in location, scale, pose, occlusion, illumination, facial expressions, and clutter ...
Samir Brahim Belhaouari   +2 more
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Combination of Evolutionary Algorithms with Experimental Design, Traditional Optimization and Machine Learning [PDF]

open access: yes, 2016
Evolutionary algorithms alone cannot solve optimization problems very efficiently since there are many random (not very rational) decisions in these algorithms.
Zhang, Qingfu
core  

Group leaders optimization algorithm [PDF]

open access: yesMolecular Physics, 2011
We present a new global optimization algorithm in which the influence of the leaders in social groups is used as an inspiration for the evolutionary technique which is designed into a group architecture. To demonstrate the efficiency of the method, a standard suite of single and multidimensional optimization functions along with the energies and the ...
Daskin, Anmer, Kais, Sabre
openaire   +4 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Comparison of Recent Meta-Heuristic Optimization Algorithms Using Different Benchmark Functions

open access: yesJournal of Mathematical Sciences and Modelling, 2022
Meta-heuristic optimization algorithms are used in many application areas to solve optimization problems. In recent years, meta-heuristic optimization algorithms have gained importance over deterministic search algorithms in solving optimization problems.
Mahmut Dirik
doaj   +1 more source

Optimal Distributed Covering Algorithms [PDF]

open access: yesProceedings of the 2019 ACM Symposium on Principles of Distributed Computing, 2019
AbstractWe present a time-optimal deterministic distributed algorithm for approximating a minimum weight vertex cover in hypergraphs of rank f. This problem is equivalent to the Minimum Weight Set Cover problem in which the frequency of every element is bounded by f. The approximation factor of our algorithm is $$(f+\varepsilon )$$
Ben-Basat, Ran   +3 more
openaire   +7 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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