Results 101 to 110 of about 2,303,688 (304)
Metals, 2019 Data generated for the Ti−Al−Cr−V system of metallic alloys from our previous publication, where the composition of 102 alloys were computationally Pareto optimized with the objective of simultaneously maximizing the Young’s ...
Rajesh Jha, George S. Dulikravich
doaj +1 more source
A modified migration model biogeography evolutionary approach for electromagnetic device multiobjective optimization [PDF]
, 2014 Inthispaper, we present anefficient androbust algorithm for multiobjective optimization of electromagnetic devices.Therecentlydeveloped biogeography-based optimization (BBO) is modified byadapting its migration model function so as to improve its ...
Dupré, Luc +2 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Metallic nanomedicine in cancer immunotherapy
Acta Pharmaceutica Sinica BImmunotherapy has become a pivotal modality in clinical cancer treatment. However, its effectiveness is limited to a small subset of patients due to the low antigenicity, impaired innate response, and various adaptive immune resistance mechanisms of the ...
Shixuan Li +8 more
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Frontiers in Microbiology, 2017 Pseudomonas aeruginosa is a Gram-negative bacterium, which causes opportunistic infections in immuno-compromised individuals. Due to its multiple resistances toward antibiotics, the development of new drugs is required.
Giuseppe Allegretta +11 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Comparison of Evolutionary Optimization Algorithms for FM-TV Broadcasting Antenna Array Null Filling [PDF]
, 2015 Broadcasting antenna array null filling is a very challenging problem for antenna design optimization. This paper compares five antenna design optimization algorithms (Differential Evolution, Particle Swarm, Taguchi, Invasive Weed, Adaptive Invasive ...
Aristotelis, Bizopoulos +7 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Stability Analysis of Neural Networks-Based System Identification
Modelling and Simulation in Engineering, 2008 This paper treats some problems related to nonlinear systems identification. A stability analysis neural network model for identifying nonlinear dynamic systems is presented.
Talel Korkobi +2 more
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source