Results 121 to 130 of about 19,096,786 (283)

Continuous Optimization of Adaptive Quadtree Structures

open access: yes, 2018
We present a novel continuous optimization method to the discrete problem of quadtree optimization. The optimization aims at achieving a quadtree structure with the highest mechanical stiffness, where the edges in the quadtree are interpreted as ...
Wu, Jun
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Research on optimization-based design [PDF]

open access: yes
Research on optimization-based design is discussed. Illustrative examples are given for cases involving continuous optimization with discrete variables and optimization with tolerances.
Balling, R. J.   +2 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Improved marine predator MPPT algorithm for photovoltaic systems in partial shading conditions

open access: yesScientific Reports
When the photovoltaic arrays are subject to partial shading (PS), their output characteristics show a multi-peak phenomenon. Under this circumstance, it will be a challenge to track the maximum power point (MPP), which impacts power generation efficiency.
Hanbo Zheng   +5 more
doaj   +1 more source

Distributed Synchronization Control to Trajectory Tracking of Multiple Robot Manipulators

open access: yesJournal of Robotics, 2011
This paper investigates the issue of designing decentralized control laws to cooperatively command a team of general fully actuated manipulators. The purpose is to synchronize their movements while tracking a common desired trajectory.
Yassine Bouteraa   +3 more
doaj   +1 more source

AI energized hydrogel design, optimization and application in biomedicine

open access: yesMaterials Today Bio
Traditional hydrogel design and optimization methods usually rely on repeated experiments, which is time-consuming and expensive, resulting in a slow-moving of advanced hydrogel development.
Zuhao Li   +6 more
semanticscholar   +1 more source

Recent developments in multilevel optimization [PDF]

open access: yes
Recent developments in multilevel optimization are briefly reviewed. The general nature of the multilevel design task, the use of approximations to develop and solve the analysis design task, the structure of the formal multidiscipline optimization ...
Kim, D.-S., Vanderplaats, Garret N.
core   +1 more source

Integrated design optimization research and development in an industrial environment [PDF]

open access: yes
An overview is given of a design optimization project that is in progress at the GE Research and Development Center for the past few years. The objective of this project is to develop a methodology and a software system for design automation and ...
German, Marjorie D.   +2 more
core   +1 more source

Design modeling for shape optimization [PDF]

open access: yes
Some important aspects of design modeling for shape optimization are discussed for both stamped sheet metal components and cast solid components. For stamped components the basis for the modeling approach is a boundary design function.
Botkin, M. E.
core   +1 more source

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