Results 141 to 150 of about 808,313 (268)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Survey on Optimization Methods for LEO-Satellite-Based Networks with Applications in Future Autonomous Transportation. [PDF]

Sensors (Basel), 2022
Çelikbilek K, Saleem Z, Morales Ferre R, Praks J, Lohan ES.   +4 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

A Review of Global Optimization Methods for Molecular Structures: Algorithms, Applications and Perspectives. [PDF]

J Comput Chem
Alvarez JAS, Calaminici P.
europepmc   +1 more source

Comparison of parameter optimization methods for quantitative susceptibility mapping. [PDF]

Magn Reson Med, 2021
Milovic C, Prieto C, Bilgic B, Uribe S, Acosta-Cabronero J, Irarrazaval P, Tejos C.   +6 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Simulation of pooling optimization methods for differing infection dynamics, sampling practices, and desired outcomes in surveillance testing. [PDF]

J Vet Diagn Invest
Burgess C, Loy DS, Loy JD, Curran A, Lahmers K.   +4 more
europepmc   +1 more source

Optimization Methods and Implementation Science: An Opportunity for Behavioral and Biobehavioral Interventions. [PDF]

Implement Res Pract, 2021
Guastaferro K, Collins LM.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Research on optimization methods for multi-energy expansion supply plans in industrial parks based on genetic algorithms. [PDF]

Sci Rep
Guo S, Wei H, Li F, Wang M, Wang D, Hong Z, Zhang C, Chen J.   +7 more
europepmc   +1 more source