Results 151 to 160 of about 799,975 (268)

Comparison of parameter optimization methods for quantitative susceptibility mapping. [PDF]

Magn Reson Med, 2021
Milovic C, Prieto C, Bilgic B, Uribe S, Acosta-Cabronero J, Irarrazaval P, Tejos C.   +6 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

A Review of Global Optimization Methods for Molecular Structures: Algorithms, Applications and Perspectives. [PDF]

J Comput Chem
Alvarez JAS, Calaminici P.
europepmc   +1 more source

Optimization Methods and Implementation Science: An Opportunity for Behavioral and Biobehavioral Interventions. [PDF]

Implement Res Pract, 2021
Guastaferro K, Collins LM.
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Simulation of pooling optimization methods for differing infection dynamics, sampling practices, and desired outcomes in surveillance testing. [PDF]

J Vet Diagn Invest
Burgess C, Loy DS, Loy JD, Curran A, Lahmers K.   +4 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Research on optimization methods for multi-energy expansion supply plans in industrial parks based on genetic algorithms. [PDF]

Sci Rep
Guo S, Wei H, Li F, Wang M, Wang D, Hong Z, Zhang C, Chen J.   +7 more
europepmc   +1 more source

Optimization methods for the imputation of missing values in Educational Institutions Data. [PDF]

MethodsX, 2021
Aureli D, Bruni R, Daraio C.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source