Results 171 to 180 of about 799,975 (268)

Elaboration of Design and Optimization Methods for a Newly Developed CFRP Sandwich-like Structure Validated by Experimental Measurements and Finite Element Analysis. [PDF]

Polymers (Basel), 2021
Kovács G.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Optimization Methods for Radon Progeny Measurement Based on the Three-Stage Method. [PDF]

Toxics
Cai X, Zeng X, Qin F, Shan J.
europepmc   +1 more source

A systematic review of emerging feature selection optimization methods for optimal text classification: the present state and prospective opportunities. [PDF]

Neural Comput Appl, 2021
Abiodun EO, Alabdulatif A, Abiodun OI, Alawida M, Alabdulatif A, Alkhawaldeh RS.   +5 more
europepmc   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Boosting biogas production through innovative data-driven modeling and optimization methods at NJWTP. [PDF]

Sci Rep
Duan J, Cao G, Ma G, Yazdani B.
europepmc   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

GOplan: an R package for animal breeding program design via integrating Gene Flow and Bayesian optimization methods. [PDF]

G3 (Bethesda)
Huang Q, Zhou L, Xue Y, Du H, Zhuo Y, Mao R, Liu Y, Yan T, Li W, Wang X, Liu J.   +10 more
europepmc   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Dosimetric Evaluation of Beam-specific PTV and Worst-case Optimization Methods for Liver Proton Therapy. [PDF]

In Vivo
Yamano A, Inoue T, Shiba S, Shimo T, Yamanaka M, Shirata R, Matsumoto K, Yagihashi T, Tokuuye K, Chang W.   +9 more
europepmc   +1 more source