Results 11 to 20 of about 90,070 (198)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Computational morphogenesis of free form shells: Filter methods to create alternative solutions [PDF]

, 2009
p. 536-547Actual trends in numerical shape optimal design of structures deal with handling of very large dimensions of design space. The goal is to allowing as much design freedom as possible while considerably reducing the modelling effort.
BLETZINGER, Kai-Uwe, FIRI, Matthias, LINHARD, Johannes, WÜCHNER, Roland   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Shape Calculus for Shape Energies in Image Processing [PDF]

, 2013
Many image processing problems are naturally expressed as energy minimization or shape optimization problems, in which the free variable is a shape, such as a curve in 2d or a surface in 3d.
Doğan, Günay
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Fundamental bounds on transmission through periodically perforated metal screens with experimental validation

, 2019
This paper presents a study of transmission through arrays of periodic sub-wavelength apertures. Fundamental limitations for this phenomenon are formulated as a sum rule, relating the transmission coefficient over a bandwidth to the static polarizability.
Ehrenborg, Casimir,, Ericsson, Andreas,, Gustafsson, Mats,, Ivanenko, Yevhen,, Jonsson, B. L.G.,, Ludvig-Osipov, Andrei,, Lund University., Lundgren, Johan,, Sjoberg, Daniel,   +8 more
core   +1 more source

The influence of orbital rotation on the energy of closed-shell wavefunctions [PDF]

, 2014
The orbital dependence of closed-shell wavefunction energies is investigated by performing doubly-occupied configuration interaction (DOCI) calculations, representing the most general class of these wavefunctions.
Ayers, Paul W, Bultinck, Patrick, De Baerdemacker, Stijn, Johnson, Paul, Kim, Taewon D, Limacher, Peter A, Van Neck, Dimitri   +6 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

3D Geometric Analysis of Tubular Objects based on Surface Normal Accumulation [PDF]

, 2015
This paper proposes a simple and efficient method for the reconstruction and extraction of geometric parameters from 3D tubular objects. Our method constructs an image that accumulates surface normal information, then peaks within this image are located ...
A Tagliasacchi, C Bauer, C Kirbas, C Xu, D Borrmann, D Lesage, E Arkin, GS Baja di, IK Lee, L Cuel, L Latecki, M Hassouna, ND Cornea, P Pare, TP Nguyen, U Bauer   +15 more
core   +6 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source