Results 31 to 40 of about 176,878,325 (207)
Regularity properties of nonlocal minimal surfaces via limiting arguments
, 2013 We prove an improvement of flatness result for nonlocal minimal surfaces which is independent of the fractional parameter s when s → 1 -.As a consequence, we obtain that all the nonlocal minimal cones are flat and that all the nonlocal minimal surfaces ...
Caffarelli, Luis +5 more
core +1 more source
Minimal Model Theory for Log Surfaces [PDF]
, 2011 We discuss the log minimal model theory for log surfaces. We show that the log minimal model program, the finite generation of log canonical rings, and the log abundance theorem for log surfaces hold true under assumptions weaker than the usual framework
Osamu Fujino, Fujino, Osamu
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Conformal and asymptotic properties of embedded genus-g minimal surfaces with one end [PDF]
, 2009 Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mathematics, 2009.Includes bibliographical references (p. 79-82).Using the tools developed by Colding and Minicozzi in their study of the structure of embedded minimal surfaces in R3 [12 ...
Bernstein, Jacob, Ph. D. Massachusetts Institute of Technology
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Optimal control of Newton-type problems of minimal resistance [PDF]
, 2006 We address Newton-type problems of minimal resistance from an optimal control perspective. It is proven that for Newton-type problems the Pontryagin maximum principle is a necessary and sufficient condition.
Plakhov, A.Yu., Torres, D.F.M.
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Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
, 2014 International audienceBecause of surface tension, soap films seek the shape that minimizes their surface energy, and thus their surface area. This mathematical postulate allows one to predict the existence and stability of simple minimal surfaces.
Pascal Panizza +7 more
core +1 more source