Results 11 to 20 of about 11,106 (181)

Modeling of Curvilinear Steel Rod Structures Based on Minimal Surfaces

open access: yes, 2021
The article deals with shaping effective curvilinear steel rod roof structures using genetic algorithms by implementing them for the analysis of various case studies in order to find new and efficient structures with positive characteristics.
Jolanta Dzwierzynska, Igor Labuda
core   +1 more source

Autonomous capillary systems for life science research and medical diagnostics [PDF]

open access: yes, 2009
In autonomous capillary systems (CS) minute amounts of liquid are transported owing to capillary forces. Such CSs are appealing due to their portability, flexibility, and the exceptional physical behavior of liquids in micrometer sized microchannels, in ...
Zimmermann, Martin
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gold nanoprobes for theranostics

open access: yes, 2011
Gold nanoprobes have become attractive diagnostic and therapeutic agents in medicine and life sciences research owing to their reproducible synthesis with atomic level precision, unique physical and chemical properties, versatility of their morphologies,
Book-Newell, Brittany   +9 more
core   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Simulations of a self propelled autonomous underwater vehicle [PDF]

open access: yes, 2010
The missions being proposed for autonomous underwater vehicles (AUVs), by both marine scientists and industry, are becoming increasingly complex and challenging.
Phillips, Alexander Brian
core  

The ALICE TPC : a large 3-dimensional tracking device with fast readout for ultra-high multiplicity events

open access: yes, 2010
The design, construction, and commissioning of the ALICE Time-Projection Chamber (TPC) is described. It is the main device for pattern recognition, tracking, and identification of charged particles in the ALICE experiment at the CERN LHC.
J. Wiechula   +318 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Investigation of mechanical properties of recycled polypropylene [PDF]

open access: yes, 2007
Every year there is an Increase in the amount of plastics formed by all types of processes, such as extrusion, blow moulding, injection moulding, etc The recycling of waste plastic materials 1s developing at a manufacturing process scale, and rts arm is ...
Elgammudi, Lutfi Furji
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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