Results 31 to 40 of about 15,096,448 (302)
Prediction-Based Planning in Production System Management through Subsystem Interaction
The research concerns the investigation of predictive models based on optimal control task. It allows increasing the management efficiency due to joint consideration and synchronization of internal and external processes towards the system. In this paper,
Mikhail Sadiakhmatov, Leonid Mylnikov
doaj +1 more source
Many discrete optimization problems are very difficult to solve on a computer; hence they are titled “intractable”. More precisely, the possible approaches to solving these problems quickly are difficult to solve (for describing algorithms, for ...
Boris Melnikov
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ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül +2 more
wiley +1 more source
We consider a general problem of optimal allocation of limited resources in a wireless telecommunication network. The network users are divided into several different groups (or classes), which correspond to different levels of service.
Igor Konnov +2 more
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A Mathematical Model of the Electrical Power Management Systems Using the Core Values in Cooperative Game [PDF]
In the context of game theory, cooperative game has been applied in several fields and can be successfully used to evaluate the players (people or companies) involved.
Mohammed Musa, Jabbar Abbas
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Profitable portfolio using fermatean fuzzy numbers [PDF]
Stock portfolio problems are one of the most relevant real-world problems. In this study, we discuss the portfolio's risk amount, rate of risk-return, and expected return rate under a Fermatean fuzzy environment.
Amal Adak, Manish Gunjan
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AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source

