Results 41 to 50 of about 7,312,623 (249)

Ant colony optimization with direct communication for the traveling salesman problem [PDF]

open access: yes, 2010
This article is posted here with permission from IEEE - Copyright @ 2010 IEEEAnts in conventional ant colony optimization (ACO) algorithms use pheromone to communicate.
Yang, S   +5 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Optimal Task Allocation Algorithm Based on Queueing Theory for Future Internet Application in Mobile Edge Computing Platform

open access: yesSensors, 2022
For 5G and future Internet, in this paper, we propose a task allocation method for future Internet application to reduce the total latency in a mobile edge computing (MEC) platform with three types of servers: a dedicated MEC server, a shared MEC server,
Yukiko Katayama, Takuji Tachibana
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Application of Optimization Algorithms in Voter Service Module Allocation

open access: yesInformation
Allocation models are essential tools for optimally distributing client requests across multiple services under defined restrictions and objective functions.
Edgar Jardón   +2 more
doaj   +1 more source

Influence of Economic Indices on the Solution to the Optimization Problem of the Age Structure of Power Plants Equipment [PDF]

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2018
In this study we consider an integral model of the large electric power system development. The model accounts for division of the generating equipment into certain age groups. Each of these groups is characterized by some efficiency coefficient.
A. S. Apartsyn   +2 more
doaj   +1 more source

The Effect of Blue Noise on the Optimization Ability of Hopfield Neural Network

open access: yesApplied Sciences, 2023
Noise is ubiquitous in the real-world environment. At present, most scholars only include the stage of Gaussian white noise when applying noise in neural networks and regard white noise as a tool to optimize the network model, which is far from enough ...
Yu Zhang   +5 more
doaj   +1 more source

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