Results 61 to 70 of about 32,124 (287)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Blockchain-Based Lightweight Trust Management in Mobile Ad-Hoc Networks
Sensors, 2020 As a trending and interesting research topic, in recent years, researchers have been adopting the blockchain in the wireless ad-hoc environment.
May Thura Lwin +2 more
doaj +1 more source
An Adaptive Relay Selection Scheme for Enhancing Network Stability in VANETs
IEEE Access, 2020 Vehicular ad hoc networks (VANETs) are a special type of wireless ad hoc network that requires highly scalable routing strategies to establishing reliable end-to-end communication.
Nori M. Al-Kharasani +3 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Design and analysis of a beacon-less routing protocol for large volume content dissemination in vehicular ad hoc networks [PDF]
, 2016 Largevolumecontentdisseminationispursuedbythegrowingnumberofhighquality applications for Vehicular Ad hoc NETworks(VANETs), e.g., the live road surveillance service and the video-based overtaking assistant service.
Baiocchi, Andrea +3 more
core +2 more sources
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Firefly-based Optimized Link State Routing Protocol for Energy-Efficient Vehicular Ad Hoc Networks
ITEGAM-JETIAVehicular ad hoc networks (VANET), a burgeoning technology within the wireless technology field, hold great promise. As it continues its progress, it stands ready to make increasingly significant contributions to advancing intelligent transportation ...
Mustafa Tareq +5 more
doaj +1 more source
A testbed for MANETs: Implementation, experiences and learned lessons [PDF]
, 2010 In this paper, we present the implementation, experiences and lessons learned of our tesbed for Ad-hoc networks and Mobile Ad hoc Networks (MANETs). We used OLSR protocol for real experimental evaluation.
Barolli, Leonard +3 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source